Protein_Domain

Part:BBa_K5310004:Design

Designed by: Ilias Pilianidis   Group: iGEM24_thessaloniki   (2024-09-29)


(Gly4Ser)4 elongated flexible linker


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

This sequence has high homologous repeats in its DNA coding sequence, and a high guanine content because of the Glycines, with all the difficulties that this entails.


Source

Argos, P. 1990 and Chen, X. et al, 2013 have suggested synthetic Glycine-Serine fusion linkers for their stability and flexibility.

References